Humanized anti-human cd34 monoclonal antibody and uses thereof
AssigneeIndustrial Technology Research Institute
InventorsWei-Chun CHIU, Min-Yuan CHOU
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Abstract
A novel humanized antibody against the CD34 surface antigen on the human stem cells is provided. The humanized antibody contains a heavy chain variable region comprising an amino sequence as set forth in SEQ ID No. 1 and a light chain variable region comprising an amino sequence as set forth in SEQ ID No. 2. The disclosure also provides the applications of the disclosed humanized antibody.
Claims24
A humanized monoclonal antibody, comprising a heavy chain variable region comprising an amino acid sequence as set forth in SEQ ID NO:
- 1 and a light chain variable region comprising an amino acid sequence as set forth in SEQ ID NO:
- 2, wherein the humanized monoclonal antibody specifically binds to a CD34 antigen on a surface of a human cell.
A humanized monoclonal antibody, comprising a heavy chain variable region comprising an amino acid sequence encoded by a nucleotide sequence as set forth in SEQ ID NO:
- 3 and a light chain variable region comprising an amino acid sequence encoded by a nucleotide sequence as set forth in SEQ ID NO:
- 4, wherein the humanized monoclonal antibody specifically binds to a CD34 antigen on a surface of a human cell.
Dependencies are inferred from the claim text.