Method for synthesizing thymosins
AssigneeBcn Peptides, S.A.
InventorsJimena FERNANDEZ CARNEADO, Berta PONSATI OBIOLS, Javier CLEMENTE RODRIGUEZ, Raimon RUBIRES FERRER, Sergi PAVON FERNANDEZ
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AssigneeBcn Peptides, S.A.
InventorsJimena FERNANDEZ CARNEADO, Berta PONSATI OBIOLS, Javier CLEMENTE RODRIGUEZ, Raimon RUBIRES FERRER, Sergi PAVON FERNANDEZ
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The invention relates to a method for obtaining thymosins and/or the pharmaceutically acceptable salts thereof by means of solid-phase synthesis on polymeric supports, which comprises the steps of linearly synthesizing the thymus-derived peptides in solid phase, incorporating at least one Thr or Ser in the sequence, in pseudoproline dipeptide form, obtaining the thymosins by treating the peptidyl resin with trifluoroacetic acid, and purifying the thymosins by RP-HPLC. The present invention also protects the isolated and/or purified compound obtained by means of said method and also the use thereof in the preparation of a medicinal product.
A method for obtaining thymosins and/or the pharmaceutically acceptable salts thereof by f solid-phase synthesis on polymeric supports wherein the method comprises the following steps:
A method for obtaining thymosins and/or the pharmaceutically acceptable salts thereof according to claim 23, where the medicinal product is for the regulation of immune response, vascular biology and cancer pathogenesis.
Dependencies are inferred from the claim text.