Dalbavancin compositions for treatment of bacterial infections
OwnerMartin Stogniewinventor
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Abstract
The invention provides methods for drying dalbavancin. The method includes providing wet dalbavancin that includes dalbavancin, water, and a solvent. The wet dalbavancin is dried at at a temperature of about 30° C. or less, at a vacuum pressure of about 50 mbar or less, until the water level of the wet dalbavancin is less than about 20% (w/w). Water is then added to the dalbavancin and the resulting wet dalbavancin is dried at least once more at a temperature of about 30° C. or less, at a vacuum pressure of about 50 mbar or less, until the solvent level of the dalbavancin is less than about 3.0% (w/w).
Claims20
A method for drying dalbavancin, comprising the steps of:
- providing wet dalbavancin comprising dalbavancin, water, and a solvent;
- drying the wet dalbavancin at a temperature of about 30° C. or less, at a vacuum pressure of about 50 mbar or less, until the water level of the wet dalbavancin is less than about 20% (w/w);
- adding water to the dalbavancin;
- and
- drying the wet dalbavancin at least once more at a temperature of about 30° C. or less, at a vacuum pressure of about 50 mbar or less, until the solvent level of the dalbavancin is less than about 3.0% (w/w).
Dependencies are inferred from the claim text.