Compositions comprising acidic extracts of mastic gum
AssigneeRegenera Pharma Ltd.
InventorsZadik Hazan, Andre C. B. Lucassen
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Abstract
The invention relates to compositions and formulations comprising isolated acidic fraction of mastic gum and uses thereof for treating impaired neurological functions as well as wound and tissue repair.
Claims29
A composition comprising an effective amount of an isolated acidic fraction of mastic gum, and a pharmaceutically acceptable carrier;
- wherein the fraction is characterized in that it is soluble in at least one polar organic solvent and in at least one non-polar organic solvent, and wherein said fraction is substantially devoid of compounds which are soluble in said polar organic solvent but insoluble in said non-polar organic solvent.
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A composition consisting essentially of a mixture of triterpenoids comprising at least three triterpenoic acids, selected from the group consisting of:
- masticadienolic acid;
- masticadienoic acid;
- isomasticadienoic acid;
- isomasticadienolic acid;
- 3-O-acetyl masticadienolic acid;
- 3-O-acetyl epimasticadienolic acid;
- 3-O-acetyl isomasticadienolic acid, 3-O-acetyl epi-isomasticadienolic acid;
- oleanonic acid;
- moronic acid;
- 3-oxo-lup-20(29)-en-28-oic acid and combinations thereof;
- and a pharmaceutically acceptable carrier for use in treating impaired neurological function.
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Dependencies are inferred from the claim text.