Cancer cell identification marker and cancer cell proliferation inhibitor
AssigneesTakayuki Mizutani, Mbc Inc., Accural Inc.
InventorsMasahiko KURODA, Masakatsu Takanashi, Kosuke Oikawa
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Abstract
Disclosed is an identification marker which can be utilized for detection of various human cancer cells and whose expression closely relates to malignant alteration of cells, and compositions for human cancer treatment which are based on suppression of cancer cell proliferation through inhibition of expression of the identification marker. The marker is human heterochromatin protein 1γ (HP1γ), and the compositions for cancer treatment comprises one or more agents which suppresses the expression of human HP1γ gene, such as siRNAs to human HP1γ.
Claims9
-19. (canceled)
A method for treatment of cancer in a mammal comprising administering, to the mammal in need thereof, an effective amount of a cancer cell proliferation inhibitor agent which is
- an siRNA which is specific to heterochromatin protein 1γ (HP1γ) gene of the mammal or
- an antisense DNA which is specific to heterochromatin protein 1γ (HP1γ) gene of the mammal.
Dependencies are inferred from the claim text.