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US 2013/0172386 A1Published application
5-ht2b receptor antagonists
AssigneeJanssen Pharmaceutica NV
InventorsJohannes Wilhelmus John F. Thuring, Luc August Laurentius Ver Donck
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Abstract
The present invention relates to novel fluorinated piperidine derivatives having antagonistic activity at the 5-HT2B receptor, pharmaceutical compositions comprising these compounds and their use as a medicine.
Claims7
A compound of Formula (I)
- or a stereochemically isomeric form thereof, wherein
- R is hydrogen or fluoro, or
- an addition salt or a solvate thereof.
A process for preparing a pharmaceutical composition as defined in claim 5, characterized in that a pharmaceutically acceptable carrier is intimately mixed with a therapeutic ally effective amount of a compound as defined in claims 1.
Dependencies are inferred from the claim text.