Trpv1 antagonists

A compound of formula (I):

• or a salt thereof, wherein:
• G is formula (i), (ii), or (iii)
• Ra is hydrogen or alkyl;
• Y1 is CH2 and Y2 is O;
• or
• Y1 is CR1aR1b, and Y2 is CH2;
• wherein R1a is hydrogen, and R1b is hydrogen or NR1cR1d wherein R1c is hydrogen or alkyl, and R1d is —(C1-C6 alkylenyl)-OH or —(C1-C6 alkylenyl)-O(alkyl), or R1c and R1d, together with the nitrogen atom to which they are attached form a monocyclic ring selected from the group consisting of morpholinyl and oxazepanyl;
• or
• Y1 is NR1 and Y2 is CH2;
• wherein R1 is hydrogen, alkyl, or —(C1-C6 alkylenyl)-OH,
• Rc is hydrogen or alkyl;
• Y3 is CR3aR3b, and Y4 is O;
• wherein R3a and R3b are each independently hydrogen or alkyl;
• or
• Y3 and Y4 are CH2;
• or
• Y3 is NR3 and Y4 is CH2;
• wherein R3 is hydrogen or alkyl;
• Rd is hydrogen or alkyl;
• Rb, at each occurrence, represents an optional substituent on the benzo moiety of the bicyclic rings of formula (i), (ii), and (iii), and is independently alkyl, halogen, or haloalkyl;
• q is 0, 1, 2, or 3;
• Z is O or S;
• X1 is CH2, O, or N(Rw) wherein Rw is hydrogen, alkyl, or haloalkyl;
• A is CH or N;
• L is a bond or CH2, and is bound to any one of the carbon atom of the ring containing X1;
• n is 1, 2, or 3;
• m is 0, 1, 2, 3, or 4;
• Rx, at each occurrence, represents optional substituent on any substitutable carbon atom of the ring containing A, and each Rx is independently alkyl, halogen, haloalkyl, OH, O(alkyl), O(haloalkyl), NH2, N(H)(alkyl), or N(alkyl)2;
• p is 0, 1, 2, 3, 4, 5, or 6;
• and
• Ry, at each occurrence, represents optional substituent on any substitutable carbon atom of the ring containing X1, and each Ry is independently alkyl, haloalkyl, —(C1-C6 alkylenyl)-O(alkyl), G1, and —(C1-C6 alkylenyl)-G1;
• wherein each G1 is the same or different, and is an aryl optionally substituted with 1, 2, 3, or 4 substituents independently selected from the group consisting of alkyl, halogen, haloalkyl, O(alkyl), and O(haloalkyl);
• two Ry groups that are attached to the same carbon atom, together with said carbon atom to which they are attached, optionally form a C3-C6 monocyclic cycloalkyl ring, wherein the monocyclic cylcoalkyl ring is optionally substituted with 1, 2, or 3 substituents independently selected from the group consisting of alkyl, oxo, halogen, and haloalkyl.