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US 2013/0172271 A1Published application
Pharmaceutical Spray Drying
OwnerCynthia Fragaleinventor
Life of this patent
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Abstract
Methods and formulations for preparing spray dried pharmaceutical products including daptomycin, azithromycin, cyclophosphamide, and voriconazole.
Claims20
A method for preparing a powdered daptomycin, azithromycin, cyclophosphamide, or voriconazole pharmaceutical formulation for injection, the method comprising:
- providing a solution comprising daptomycin, azithromycin, cyclophosphamide, or voriconazole and polyethylene glycol (PEG);
- and
- spray drying the solution to form a powder that can be reconstituted and administered by IV infusion.
The method of claim 12, further comprising transferring the powder under positive pressure to a pressurized vessel.
A method for preparing a powdered azithromycin formulation for injection, the method comprising:
- providing a solution comprising azithromycin and citric acid;
- and
- spray drying the solution to form a powder that can be reconstituted and administered by IV infusion.
A method for preparing a powdered daptomycin formulation for injection, the method comprising:
- providing a solution comprising daptomycin and citric acid;
- and
- spray drying the solution to form a powder that can be reconstituted and administered by IV infusion.
Dependencies are inferred from the claim text.