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US 2013/0172264 A1Published application
Inhibitors of iap
AssigneeGenentech, Inc.
InventorsFrederick COHEN, Michael KOEHLER, Lewis J. GAZZARD, Vickie Hsiao-Wei TSUI
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Abstract
Novel inhibitors of IAP that are useful as therapeutic agents for treating malignancies and have the general formula I: wherein R1,R2,R3,R4,R5 and R6 are as described herein.
Claims22
A compound of formula I
- wherein
- Ph is phenyl;
- R1 is C3-7 cycloalkyl;
- R2, R3, R4, R5, and R6are each independently in each occurrence H or C1-6 alkyl;
- or a pharmaceutically acceptable salt thereof.
2 more elements
A method for treating a disease or condition associated with the overexpression of an IAP in a mammal, comprising administering to said mammal an effective amount of a compound of claiml.
A method for treating a disease or condition associated with the overexpression of an IAP in a mammal, comprising administering to said mammal an effective amount of a compound of claim2.
Dependencies are inferred from the claim text.