Arrays and Methods of Use
AssigneeSingular Bio, Inc.
InventorKalim Mir
Life of this patent
Estimating the term…
Abstract
Methods are provided for producing a molecular array comprising a plurality of molecules immoblised to a solid substrate at a density which allows individual immobilised molecules to be individually resolved, wherein each individual molecule in the array is spatially addressable and the identity of each molecule is known or determined prior to immobilisation. The use of spatially addressable low density molecular arrays in single molecule detection and analysis techniques is also provided. Novel assays and methods are also provided.
Claims12
1-3. (canceled)
A method for producing a molecular array wherein molecules on the array can be individually resolved which method comprises:
- (i) providing a molecular array comprising a plurality of functional molecules of known identity immobilised to a solid phase;
- and
- (ii) labeling only a portion the density of functional immobilised molecules in the array such that remaining labeled individual functional immobilised molecules are spatially addressable and capable of being individually resolved by optical methods.
5-16. (canceled)
18-19. (canceled)
22-23. (canceled)
27-107. (canceled)
Dependencies are inferred from the claim text.