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US 2013/0172200 A1Published application
Method of assessing cancerous conditions and reagent for detecting gene product to be used in the method
AssigneeSekisui Medical Co., Ltd.
InventorsMasato MAEKAWA, Takeshi Uramoto
Life of this patent
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Abstract
A reagent for detecting gene product, the reagent comprising a probe or chemical modulation that specifically binds to an alternative splicing junction of a gene product of human PTCH1 gene, the expression of the gene product from gene products of the human PTCH1 gene being varied due to the unusual alternative splicing, for use for measuring the abundance of the gene product contained in a human sample.
Claims11
1-19. (canceled)
A method of determining a cancerous tissue from a human sample, the method comprising:
- (1) measuring an abundance of at least one transcription product of human patched homolog 1 (PTCH1) gene contained in the sample, wherein the transcription product of which the abundance is measured contains, in an RNA sequence thereof, at least one base sequence selected from the group consisting of SEQ ID NO:1, SEQ ID NO:2, SEQ ID NO:3, and SEQ ID NO:4;
- and
- (2) determining cancerous tissue of the human sample with the measured abundance of the transcription product in the human-derived sample as an index.
Dependencies are inferred from the claim text.