Back to results
US 2013/0171732 A1Published application
Methods and compositions for regulating hiv infection
AssigneeSangamo BioSciences, Inc.
InventorsMichael C. Holmes, Philip D. Gregory, Fyodor Urnov
Life of this patent
Estimating the term…
Abstract
Methods and compositions for regulating HIV infection and/or replication in which an anti-HIV transgene is integrated into the genome of a cell using a nuclease.
Claims12
A method of inhibiting HIV infection or replication in a cell, the method comprising:
- introducing an anti-HIV transgene into a target site in the genome of the cell, wherein the anti-HIV transgene is integrated into the genome following double-stranded cleavage of the target site by a non-naturally occurring zinc finger nuclease (ZFN), and further wherein the anti-HIV transgene is expressed in the cell, thereby inhibiting HIV infection or replication.
Dependencies are inferred from the claim text.