Highly stable beta-class carbonic anhydrases useful in carbon capture systems
AssigneeCodexis, Inc.
InventorsOscar Alvizo, Michael R. Benoit, Scott J. Novick
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Abstract
The present disclosure relates to β-class carbonic anhydrase polypeptides having improved properties including increased thermostability and/or stability in the presence of amine compounds, ammonia, or carbonate ion. The present disclosure also provides formulations and uses of the polypeptides for accelerating the absorption of carbon dioxide from a gas stream into a solution as well as for the release of the absorbed carbon dioxide for further treatment and/or sequestering. Also provided are polynucleotides encoding the carbonic anhydrase polypeptides and host cells capable of expressing them.
Claims21
1-49. (canceled)
A recombinant carbonic anhydrase polypeptide comprising an amino acid sequence having at least 80% identity to SEQ ID NO:
- 2 and comprising an amino acid residue difference relative to SEQ ID NO:
- 2 at a position selected from X30, X40, X84, X96, X120, X121, X139, and X147.
Dependencies are inferred from the claim text.