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AssigneeKyowa Medex Co., Ltd.
InventorsTomomi Murakami, Haruyo Soya, Yu Ohsugi, Ayako Yoda, Haruki Tsunoda, Masashi Matsushita
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It is to provide a method for measuring glycated hemoglobin in a hemoglobin-containing sample, comprising reacting the hemoglobin-containing sample with a proteolytic enzyme in the presence of a surfactant, and then reacting the obtained reaction product with fructosyl peptide oxidase, wherein at least one of the former reaction and the latter reaction is performed in the presence of an isothiazolinone derivative; and measuring the generated hydrogen peroxide. The present invention provides a method for accurately and highly sensitively measuring glycated hemoglobin in a hemoglobin-containing sample without being influenced by hemoglobin.
A method for measuring glycated hemoglobin in a hemoglobin-containing sample, comprising reacting the hemoglobin-containing sample with a proteolytic enzyme in the presence of a surfactant, and then reacting the obtained reaction product with fructosyl peptide oxidase, wherein at least one of the former reaction and the latter reaction is performed in the presence of an isothiazolinone derivative;
A reagent for measuring glycated hemoglobin in a hemoglobin-containing sample, comprising a proteolytic enzyme, fructosyl peptide oxidase, an isothiazolinone derivative, and a surfactant.
A kit for measuring glycated hemoglobin in a hemoglobin-containing sample comprising:
A kit for measuring glycated hemoglobin in a hemoglobin-containing sample comprising:
Dependencies are inferred from the claim text.