Nanop article-oligonucleotide hybrid structures and methods of use thereof
AssigneeThe Trustees of the University of Pennsylvania
InventorsSo Jung Park, Xi-Jun Chen
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Abstract
The invention relates to hybrid structures comprising an amphiphilic nucleic acid-block co-polymer assembly on the exterior and a nanoparticle core, and methods of use thereof.
Claims33
A nanoparticle-nucleic acid hybrid structure, comprising a high density oligonucleotide-amphiphilic block co-polymer exterior assembly and a hydrophobic nanoparticle core.
A method for delivering a composition to a cell, the method comprising providing a nanoparticle-nucleic acid hybrid structure that comprises a high density oligonucleotide-amphiphilic block co-polymer exterior assembly and a hydrophobic nanoparticle core.
Dependencies are inferred from the claim text.