Porous membranes having a polymeric coating and methods for their preparation and use

A method for preparing a modified porous membrane comprising:

• a) providing an unmodified porous membrane;
• b) exposing the porous membrane to e-beam radiation;
• c) immersing the porous membrane in a solution of a poly (A)x-linkage-B;
• d) wherein A is an e-beam reactive moiety, wherein poly (A)x is a polymer of the e-beam reactive moiety and x is a number of A monomers present in the poly (A)x polymer;
• and wherein the linkage forms a bond between the poly (A)x polymer and a B group;
• e) drying the porous membrane, and thereby preparing a modified porous membrane.

A method for preparing a modified solid phase material comprising:

• a) providing an unmodified solid phase material;
• b) immersing the solid phase material in a solution of a poly (A)x-linkage-B;
• c) wherein A is an e-beam reactive moiety, wherein poly (A)x is a polymer of the e-beam reactive moiety and x is a number of A monomers present in the poly (A)x polymer;
• and wherein the linkage forms a bond between the poly (A)x polymer and a B group;
• d) exposing the solid phase material to e-beam radiation;
• e) drying the solid phase material, and thereby preparing a modified solid phase material.