Solid dispersion preparation
AssigneeShin-Etsu Chemical Co., Ltd.
InventorsTakafumi HOSHINO, Fumie KUSAKI, Ikuo FUKUI
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AssigneeShin-Etsu Chemical Co., Ltd.
InventorsTakafumi HOSHINO, Fumie KUSAKI, Ikuo FUKUI
Estimating the term…
A granule or a tablet of a solid dispersion that allows a drug in a preparation to be rapidly dissolved without impairing dissolving of the solid dispersion, and a method for producing same is composed of 1 to 10% by weight of a poorly soluble drug, a water-soluble polymer, an excipient and 15 to 50% by weight if a disintegrator; a tablet of a solid dispersion composed of a poorly soluble drug, 1 to 5% by weight of a water-soluble polymer, an excipient and 15 to 50% by weight of a disintegrator; and a method for producing a granule or tablet of a solid dispersion comprising spraying a water-soluble polymer solution, in which a poorly soluble drug has been dispersed or dissolved, on a mixed powder of an excipient and a disintegrator, and granulating and drying a resultant.
A method for producing a tablet of a solid dispersion, comprising steps of:
Dependencies are inferred from the claim text.