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US 2013/0171261 A1Published application
Process for Preparing Cyclic Esters Comprising Unsaturated Functional groups And Polyesters Prepared From Same
AssigneeEvonik Degussa GmbH
InventorsPeter Markland, Xi Zhang
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Abstract
Disclosed herein are process for preparing cyclic esters comprising unsaturated functional groups. Also disclosed are copolymers prepared from the cyclic esters. The copolymers can be used to form microparticles, polymer micelles, etc., which are useful in drug delivery applications.
Claims11
1-16. (canceled)
A copolymer having the formula:
- wherein n and m are each independent integers ranging from 1 to 10,000;
- wherein x is an integer ranging from 0 to 12;
- wherein each R1a and each R1b, when present, is independently hydrogen, hydroxy, amino, thio, halogen, substituted or unsubstituted C1-C6 alkyl, substituted or unsubstituted C1-C6 alkoxy, substituted or unsubstituted C1-C6 alkylthio, substituted or unsubstituted C1-C6 alkylamino, or substituted or unsubstituted C1-C6 hydroxyalkyl;
- wherein R2 is hydrogen, hydroxy, amino, thio, halogen, substituted or unsubstituted C1-C6 alkyl, substituted or unsubstituted C1-C6 alkoxy, substituted or unsubstituted C1-C6 alkylthio, substituted or unsubstituted C1-C6 alkylamino, or substituted or unsubstituted C1-C6 hydroxyalkyl;
- wherein Q1 is —COOH or
- and
- wherein Q2 is —[(CH)CH3]—, —(CH2)—, or —[(CH2)5]—.
4 more elements
Dependencies are inferred from the claim text.