Enzymatic peracid generation for use in skin care products

A method to provide a peracid benefit agent to skin comprising:

• a) providing a set of reaction components comprising:
• 1) at least one enzyme having perhydrolytic activity;
• 2) a source of peroxygen;
• and
• 3) a substrate selected form the group consisting of
• i) esters having the structure
• [X]mR5
• wherein X=an ester group of the formula R6C(O)O
• R6=C1 to C7 linear, branched or cyclic hydrocarbyl moiety, optionally substituted with hydroxyl groups or C1 to C4 alkoxy groups, wherein R6 optionally comprises one or more ether linkages for R6=C2 to C7;
• R5=a C1 to C6 linear, branched, or cyclic hydrocarbyl moiety or a five-membered cyclic heteroaromatic moiety or six-membered cyclic aromatic or heteroaromatic moiety optionally substituted with hydroxyl groups;
• wherein each carbon atom in R5 individually comprises no more than one hydroxyl group or no more than one ester group or carboxylic acid group;
• wherein R5 optionally comprises one or more ether linkages;
• m is an integer ranging from 1 to the number of carbon atoms in R5;
• and
• wherein said esters have solubility in water of at least 5 ppm at 25° C.;
• ii) glycerides having the structure
• wherein R1=C1 to C7 straight chain or branched chain alkyl optionally substituted with an hydroxyl or a C1 to C4 alkoxy group and R3 and R4 are individually H or R1C(O);
• iii) one or more esters of the formula
• wherein R1 is a C1 to C7 straight chain or branched chain alkyl optionally substituted with an hydroxyl or a C1 to C4 alkoxy group and R2 is a C1 to C10 straight chain or branched chain alkyl, alkenyl, alkynyl, aryl, alkylaryl, alkylheteroaryl, heteroaryl, (CH2CH2O)n, or (CH2CH(CH3)—O)nH and n is 1 to 10;
• and
• iv) acetylated saccharides selected from the group consisting of acetylated monosaccharides, acetylated disaccharides, and acetylated polysaccharides;
• and
• v) mixtures thereof;
• and
• 4) a dermally acceptable carrier medium;
• and
• 5) a source of water;
• b) contacting a body surface comprising skin with an effective amount of an enzymatically generated peracid obtained by combining the set of reaction components;
• whereby a peracid-based benefit is provided to the body surface comprising skin;
• c) optionally rinsing the body surface;
• d) optionally drying the rinsed body surface;
• e) optionally repeating steps (a) through (d).

A method to provide an enzymatically generated peracid benefit agent to skin comprising:

• a) providing a composition comprising a population of enzymes having perhydrolytic activity;
• said enzymes having at least one binding domain having affinity for skin;
• b) contacting a body surface comprising skin with the composition of step a), whereby a first fraction of the population of enzymes binds durably to skin and a second fraction of the population of enzymes does not durably bind to skin;
• c) optionally rinsing the body surface to remove the second fraction of enzymes not durably bound to skin;
• d) optionally drying the rinsed body surface;
• e) contacting said enzymes durably bound to skin with
• 1) a source of peroxygen;
• 2) at least one carboxylic acid ester substrate;
• 3) a source of water;
• whereby a peracid benefit agent is enzymatically generated and contacted with the skin, providing a peracid-based benefit to skin;
• and
• f) optionally repeating steps (a) through (e).