Pharmaceutical Compositions
AssigneeViiV Healthcare Company
InventorsDeepak B. Mundhra, Rennan Pan
Life of this patent
Estimating the term…
Abstract
The present Invention relates to pharmaceutical compositions of (3S,11aR)-N-[(2,4-difluorophenyl)methyl]-2,3,5,7,11,11a-hexahydro-6-hydroxy-3-methyl-5,7-dioxo-oxazolo[3,2-a]pyrido[1,2-d]pyrazine-8-carboxamide, useful in the treatment or prevention of Human Immunodeficiency Virus (HIV) infections.
Claims22
A parenteral pharmaceutical composition comprising a compound of formula (I)
- or a pharmaceutically acceptable salt thereof, and a surfactant system comprising a polysorbate and polyethylene glycol.
(canceled)
(canceled)
A parenteral pharmaceutical composition for administration once every one to three months, comprising 0.1-50% by weight of a compound of formula (I)
- 0.1-10% polysorbate 20, and 0.1-10% polyethylene glycol, and wherein the mean particle size of said composition is 0.1-1.0 μm.
A combination of a parenteral pharmaceutical composition for administration once every 1 to 3 months comprising a compound of formula (I)
- and rilpivirine hydrochloride.
Dependencies are inferred from the claim text.