Feline picorna virus and uses thereof

An isolated nucleic acid comprising from 10 to 7490 consecutive nucleotides selected from:

• SEQ ID NO:
• 1, a sequence complementary to SEQ ID NO:
• 1, a sequence having about 85% identity to SEQ ID NO:
• 1, or a sequence having about 85% identity to a sequence complementary to SEQ ID NO:
• 1, wherein the % identity is determined by analysis with a sequence comparison algorithm.

An isolated nucleic acid comprising 10 to 30 consecutive nucleotides selected from SEQ ID NO:

• 19, positions 1 to 372 of SEQ ID NO:
• 1, which is the 5′UTR of SEQ ID NO:
• 1, SEQ ID NO:
• 20, positions 2962 to 7490 of SEQ ID NO:
• 1, SEQ ID NO:
• 21, positions 6007 to 7389 of SEQ ID NO:
• 1, or a sequence complementary to SEQ ID NOs:
• 19, 20, or 21.

An isolated antibody that specifically binds to FeSV encoded by SEQ ID NO:

• 1 or a degenerate variant of SEQ ID NO:
• 1, or binds to a component derived from the FeSV encoded by SEQ ID NO:
• 1 or a degenerate variant of SEQ ID NO:
• 1.

An isolated antibody which binds to one or more of P1, (SEQ ID NO:

• 8), VP1 (SEQ ID NO:
• 7), VP2, (SEQ ID NO:
• 5), VP3 (SEQ ID NO:
• 6), or VP4 (SEQ ID NO:
• 4) of FeSV.

A method for determining the presence or absence of FeSV in a biological sample, the method comprising:

• a) contacting a biological sample with an antibody that specifically binds to a FeSV;
• P1, VP1, VP2, VP3 or VP4 polypeptide encoded by SEQ ID NO:1;
• or any combination thereof, and
• b) determining whether or not the antibody binds to an antigen in the biological sample, wherein binding indicates that the biological sample contains FeSV.