Soluble Forms of Hendra and Nipah Virus G Glycoprotein
AssigneeThe Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc.
InventorsChristopher C. Broder, Katharine N. Bossart
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Abstract
This invention relates to soluble forms of G glycoprotein from Hendra and Nipah virus. In particular, this invention relates to compositions comprising soluble forms of G glycoprotein from Hendra and Nipah virus and also to diagnostic and therapeutic methods using the soluble forms of G glycoprotein from Hendra and Nipah virus. Further, the invention relates to therapeutic antibodies including neutralizing antibodies, and vaccines for the prevention and treatment of infection by Hendra and Nipah viruses.
Claims25
-40. (canceled)
A peptide comprising a soluble form of the G protein, or a fragment, analog or homolog thereof, which is derived from Hendra virus.
A method of detecting infection by a Hendra virus comprising detecting Hendra virus antigens or antibodies to Hendra virus in a sample obtained from a subject suspected of being infected.
A peptide comprising a soluble form of the G protein, or a fragment, analog or homolog thereof, which is derived from Nipah virus.
A method of detecting infection by a Nipah virus comprising detecting Nipah virus antigens or antibodies to Nipah virus in a sample obtained from a subject suspected of being infected.
Dependencies are inferred from the claim text.