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US 2013/0171129 A1Published application
Constrained immunogenic compositions and uses therefor
OwnerFasseli Joseph Coulibaly, Ashley Scott Mansell +1inventors
InventorsFasseli Joseph Coulibaly, Ashley Scott Mansell, Rosemary Ann Ffrench
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Abstract
A stable immunogenic or vaccine composition comprising a complex or polyhedra comprising same comprising an antigen of a pathogen or other antigen against which a immune response is sought in a human or non-human animal subject and a polyhedrin protein derived from a cytoplasmic polyhedrosis virus (CPV), Delivery of the complex to a subject in substantially polyhedral form induces an immune response thereto. Methods of using same to elicit an immune response.
Claims15
A stable immunogenic or vaccine composition, comprising a complex comprising:
- an antigen of a pathogen or other antigen against which an immune response is sought in a human or non-human animal subject;
- and
- a polyhedrin protein derived from a cytoplasmic polyhedrosis virus (CPV), wherein delivery of the complex to a subject in substantially particulate polyhedral form induces an immune response thereto.
Dependencies are inferred from the claim text.