Healing powder and method of use thereof
OwnerPhilip A. Marracciniinventor
Life of this patent
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Abstract
A wound healing powder, comprising a sugar selected from the group consisting of one or more pharmaceutically acceptable monosaccharides and disaccharides, in an amount of at least 25% by weight of the powder mixture; and an absorbent agent which forms a bioabsorbable biocompatible matrix with wound secretions, comprising a polymer formed of one or more of saccharide or saccharide derivative monomers and lactic acid monomers, in an amount of at least 25% by weight of the powder mixture.
Claims20
A pharmaceutically acceptable dry powder formulation adapted for administration to external wounds of the skin which have wound secretions, to promote tissue regeneration and functional microvasculature, comprising:
- a first component comprising a sufficient amount of one or more pharmaceutically acceptable monosaccharides or disaccharides to form and maintain an antibacterial environment resulting from a low water activity and a high osmotic pressure due to partial dissolution of the first component;
- and
- a second component comprising at least one of a starch and polylactic acid, forming a biocompatible and bioabsorbable matrix,
- wherein the pharmaceutically acceptable dry powder is adapted to adhere and cake on the external surface of the wound, and to absorb would secretions from the wound.
A pharmaceutically acceptable dry powder formulation adapted for administration to the skin, comprising:
- a sufficient amount of one or more pharmaceutically acceptable monosaccharides or disaccharides to absorb would secretions from the wound to form and maintain an antibacterial environment proximate to the wound resulting from a low water activity and a high osmotic pressure due to hydration of the one or more pharmaceutically acceptable monosaccharides or disaccharides with wound secretions;
- and
- a sufficient amount of at least one of a starch and polylactic acid, which is adapted to form a biocompatible and bioabsorbable matrix proximate to the wound to facilitate tissue regeneration, the dry powder being adapted to adhere and cake on the external surface of the wound, forming a self-adherent dressing.
Dependencies are inferred from the claim text.