Back to results
US 2013/0171067 A1Published application
TECHNETIUM-99m COMPLEX AS A TOOL FOR THE IN VIVO DIAGNOSIS OF CANCEROUS TUMOURS
AssigneePierre Fabre Medicament
InventorsYves Guminski, Thierry Imbert, Sabrina Pesnel, Nicolas Guilbaud, Alain Le Pape, Stéphanie Lerondel
Life of this patent
Estimating the term…
Abstract
The invention relates to a compound having formula (I), compositions containing same and preparation methods thereof. The invention also relates to a complex of the compound having formula (I) with technetium-99m and tricine, the use of this complex as a diagnostic probe, diagnostic compositions containing same and methods for preparing the complex and compositions containing same.
Claims26
-16. (canceled)
A compound having the following formula (I):
- wherein:
- R1 represents a hydrogen atom or an N-protecting group,
- R2 represents a hydrogen atom, an optionally fluorinated or perfluorinated C1-6alkyl group, or an amino-C1-6alkyl group,
- a, b and c represent, independently of each other, an integer from 2 to 5, and
- d and e represent, independently of one another, 1 or 2,
- or a pharmaceutically acceptable salt thereof.
3 more elements
A complex having the following formula (II):
- wherein:
- technetium (Tc) is present in the form of the 99m isotope thereof,
- R2 represents a hydrogen atom, an optionally fluorinated or perfluorinated C1-6alkyl group, or an amino-C1-6alkyl group,
- a, b and c represent, independently of each other, an integer from 2 to 5, and
- d and e represent, independently of one another, 1 or 2,
- or a pharmaceutically acceptable salt thereof.
3 more elements
Dependencies are inferred from the claim text.