# US 2013/0158652 A1 · Medical implants > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 2013/0158652 A1 - Document ID: US20130158652A1 - Status: Published application - Kind: A1 - Application number: 13/766,294 - Filed: 2013-02-13 - Published: 2013-06-20 - Earliest claimed: 2011-02-22 - Assignees: 480 Biomedical, Inc. - Inventors: Maria Palasis; Changcheng You; Daniel Concagh; Lee Core; Kicherl Ho; Upma Sharma; Greg Zugates - Web page: https://patentgrep.com/patent/US20130158652A1 ## CPC - A61F 2/82: Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents (stent-grafts for tubular structures of the body other than blood vessels A61F2/04; stent-grafts for blood vessels A61F2/07) - A61F 2/90: characterised by a net-like or mesh-like structure - A61L 29/06: obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds - A61L 29/085: {Macromolecular materials} - A61L 29/16: Biologically active materials, e.g. therapeutic substances {(A61L29/048 takes precedence)} - A61L 31/10: Macromolecular materials - A61L 31/14: Materials characterised by their function or physical properties {, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials} - A61F 2230/0054: V-shaped - A61F: FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS (dental prosthetics A61C) - A61L: METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES (preservation of bodies or disinfecting characterised by the agents employed A01N; preserving, e.g. sterilising, food or foodstuffs A23; preparations for medical, dental or toiletry purposes A61K) ## Abstract Disclosed are self-expanding medical implants for placement within a lumen of a patient. The implants comprise a woven or non-woven structure having a substantially tubular configuration, and are designed to be low-profile such that they are deliverable with a small diameter catheter. The implants have a high recoverability and desired mechanical properties. ## Claims ### Claim 1 A medical implant comprising: a tubular structure being characterized by a first diameter and comprising a first polymeric material; a conformal coating comprising a second polymeric material, said coating at least partially coating said tubular structure; wherein said tubular structure is characterized by a radial resistive force that does not decrease by more than 50% after being placed into a configuration that is 55% to 90% of said first diameter in an aqueous environment at 37° C. for eight weeks. ### Claim 2 (depends on 1) The medical implant of claim 1, wherein said second polymeric material is a thermoset elastomer. ### Claim 3 (depends on 2) The medical implant of claim 2, wherein said thermoset elastomer is a polyester urethane. ### Claim 4 (depends on 3) The medical implant of claim 3, wherein the thermoset elastomer is poly (lactic acid-co-caprolactone). ### Claim 5 (depends on 4) The medical implant of claim 4, wherein said poly (lactic acid-co-caprolactone) comprises about 50 weight percent of lactic acid and about 50 weight percent of caprolactone. ### Claim 6 (depends on 2) The medical implant of claim 2, wherein said thermoset elastomer is prepared by a process that comprises the steps of: at least partially dissolving a polyester polymer in a solvent to form a solution; adding a diisocyanate crosslinker to said solution; adding a chain terminator to said solution; and curing said solution. ### Claim 7 (depends on 6) The medical implant of claim 6, wherein said diisocyanate crosslinker is hexamethylene diisocyanate. ### Claim 8 (depends on 6) The medical implant of claim 6, wherein said chain terminator comprises a monoisocyanate. ### Claim 9 (depends on 8) The medical implant of claim 8, wherein said monoisocyanate is 1-dodecylisocyanate. ### Claim 10 (depends on 6) The medical implant of claim 6, wherein said chain terminator comprises a monoalcohol. ### Claim 11 (depends on 10) The medical implant of claim 10, wherein said monoalcohol is 1-dodecanol. ### Claim 12 (depends on 2) The medical implant of claim 2, wherein said first polymeric material comprises poly(lactic acid co-glycolic acid). ### Claim 13 (depends on 6) The medical implant of claim 6, wherein said thermoset elastomer comprises at least 1.5 wt % of said chain terminator. ### Claim 14 (depends on 13) The medical implant of claim 13, wherein said thermoset elastomer comprises at least 2.0 wt % of said chain terminator. ### Claim 15 (depends on 13) The medical implant of claim 13, wherein said thermoset elastomer comprises at least 4.0 wt % of said chain terminator. ### Claim 16 (depends on 1) The medical implant of claim 1, wherein said tubular structure is characterized by a chronic outward force that does not decrease by more than 50% after being placed into a configuration that is 55% to 90% of said first diameter in an aqueous environment at 37° C. for twelve weeks. ### Claim 17 (depends on 1) The medical implant of claim 1, wherein said tubular structure is characterized by a radial resistive force that does not decrease by more than 50% after being placed into a configuration that is not greater than 75% of said first diameter in an aqueous environment at 37° C. for twelve weeks. ### Claim 18 (depends on 17) The medical implant of claim 17, wherein said tubular structure is characterized by a chronic outward force that does not decrease by more than 50% after being placed into a configuration that is not greater than 75% of said first diameter in an aqueous environment at 37° C. for twelve weeks. ### Claim 19 (depends on 1) The medical implant of claim 1, wherein said tubular structure is characterized by a chronic outward force that does not decrease by more than 25% after being placed into a configuration that is 55% to 90% of said first diameter in an aqueous environment at 37° C. for eight weeks.