Mutant microorganism having high production of cadaverine, and preparation method of cadaverine using same

A mutant microorganism having the ability to produce cadaverine wherein at least one gene selected from the group consisting of a speE gene encoding putrescine/cadaverine aminopropyl transferase, a speG gene encoding spermidine N-acetyltransferase, a ygjG gene encoding putrescine/cadaverine aminotransferase, a puuP gene encoding putrescine importer and a puuA gene encoding glutamate-putrescine/glutamate-cadaverine ligase, which are involved in the cadaverine degradation or utilization pathway, is inactivated or deleted, and wherein a native promoter of at least one gene selected from the group consisting of a dapA gene encoding dihydrodipicolinate synthase, a lysA gene encoding diaminopimelate decarboxylase, and a dapB gene encoding dihydrodipicolinate reductase is replaced with a strong promoter.

-17. (canceled)

A method for preparing a mutant microorganism having the ability to produce cadaverine, the method comprising:

• inactivating or deleting at least one gene selected from the group consisting of a speE gene encoding putrescine/cadaverine aminopropyl transferase, a speG gene encoding spermidine N-acetyltransferase, a ygjG gene encoding putrescine/cadaverine aminotransferase, a puuP gene encoding putrescine importer, and a puuA gene encoding glutamate-putrescine/glutamate-cadaverine ligase, which are involved in the cadaverine degradation or utilization pathway, from a microorganism having a cadaverine production pathway.

A method for preparing a mutant microorganism having the ability to produce cadaverine, the method comprising:

• inactivating or deleting at least one gene selected from the group consisting of a speE gene encoding putrescine/cadaverine aminopropyl transferase, a speG gene encoding spermidine N-acetyltransferase, a ygjG gene encoding putrescine/cadaverine aminotransferase, a puuP gene encoding putrescine importer, and a puuA gene encoding glutamate-putrescine/glutamate-cadaverine ligase, which are involved in the cadaverine degradation or utilization pathway, from a microorganism having a cadaverine production pathway;
• and replacing a native promoter of at least one gene selected from the group consisting of a dapA gene encoding dihydrodipicolinate synthase, a lysA gene encoding diaminopimelate decarboxylase, and a dapB gene encoding dihydrodipicolinate reductase, which are present in the microorganism having the cadaverine production pathway, with a strong promoter.

-34. (canceled)