# US 2013/0157291 A1 · DIAGNOSTIC MARKER FOR LUNG CANCER COMPRISING HPaR AS ACTIVE INGREDIENT

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- Number: US 2013/0157291 A1
- Document ID: US20130157291A1
- Status: Published application
- Kind: A1
- Application number: 13/514,668
- Filed: 2011-06-29
- Published: 2013-06-20
- Earliest claimed: 2011-06-29
- Assignees: Paichai University-Academic Cooperation Foundation
- Inventors: Il Han Kim
- Web page: https://patentgrep.com/patent/US20130157291A1

## CPC

- G01N 33/6884: {from lung}
- C07K 16/18: against material from animals or humans
- G01N 33/5752: of the lungs
- G01N: INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES (measuring or testing apparatus or processes other than immunoassay, involving enzymes or microorganisms C12M, C12Q)
- C07K: PEPTIDES (peptides in foodstuffs A23; obtaining protein compositions for foodstuffs, working-up proteins for foodstuffs A23J; preparations for medicinal purposes A61K; peptides containing beta-lactam rings C07D; cyclic dipeptides not having in their molecule any other peptide link than those which form their ring, e.g. piperazine-2,5-diones, C07D; ergot alkaloids of the cyclic peptide type C07D519/02; macromolecular compounds having statistically distributed amino acid units in their molecules, i.e. when the preparation does not provide for a specific; but for a random sequence of the amino acid units, homopolyamides and block copolyamides derived from amino acids C08G69/00; macromolecular products derived from proteins C08H1/00; preparation of glue or gelatine C09H; single cell proteins, enzymes C12N; genetic engineering processes for obtaining peptides C12N15/00; compositions for measuring or testing processes involving enzymes C12Q; investigation or analysis of biological material G01N33/00)

## Abstract

Disclosed is a diagnostic marker for lung cancer comprising HpαR as an active ingredient. Because blood, which is relatively easy to sample, is employed as a specimen, the diagnostic kit and marker for lung cancer is very simple and does not subject patients to a load compared to conventional methods that are directed to a biopsy. In addition, the kit and marker of the present invention is useful in the early diagnosis of lung cancer thanks to its high diagnostic sensitivity and selectivity.

## Claims

### Claim 1

A diagnostic marker for lung cancer, comprising HpαR as an active ingredient.

### Claim 2

A diagnostic kit for lung cancer, comprising an antibody specifically binding to HpαR.

### Claim 3

A method for diagnosing lung cancer, comprising measuring the concentration of HpαR in a blood sample.

### Claim 4 (depends on 3)

The method of claim 3, wherein the blood sample is a serum.