# US 2013/0156868 A1 · Nasal spray

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- Number: US 2013/0156868 A1
- Document ID: US20130156868A1
- Status: Published application
- Kind: A1
- Application number: 13/817,539
- Filed: 2011-09-01
- Published: 2013-06-20
- Earliest claimed: 2010-09-07
- Assignees: Krewel Mueselbach GmbH
- Inventors: Detlef Schierstedt
- Web page: https://patentgrep.com/patent/US20130156868A1

## CPC

- A61K 36/534: Mentha (mint)
- A61K 9/0043: {Nose}
- A61K 9/08: Solutions {(composition of solutions A61K47/00)}
- A61K 31/045: Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K 31/164: of a carboxylic acid with an aminoalcohol, e.g. ceramides
- A61K 31/74: Synthetic polymeric materials
- A61K 33/14: Alkali metal chlorides; Alkaline earth metal chlorides
- A61K 36/53: Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K 36/61: Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
- A61K 47/38: Cellulose; Derivatives thereof
- A61P 11/00: Drugs for disorders of the respiratory system
- A61P 11/02: Nasal agents, e.g. decongestants
- A61P 29/00: Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P 37/08: Antiallergic agents (antiasthmatic agents A61P11/06; ophthalmic antiallergics A61P27/14)
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A61P: SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

## Abstract

The invention relates to a medicinal product which is free from sympathomimetics, has an advantageous effect on the nasal mucosa in case of common colds, hay fever, dry nose and sympathomimetic dependencies, and is provided in the form of a nasal spray, a nasal douche or nasal drops.

## Claims

### Claim 1

A sympathomimetic-free medicinal product in the form of drops, spays, and/or rinses for use for preparing an agent for treating irritations of the nasal mucosa by a cold, by hay fever, a dry nose and/or sympathomimetic dependence, characterized by comprising menthol, mint oil and/or camphor as well as at least one humectant comprising water-soluble or water-dispersible natural or synthetic polymers that form gels or viscous solutions in aqueous systems, polyhydric alcohols, mono-, di- and/or polysaccharides.

### Claim 2 (depends on 1)

The sympathomimetic-free medicinal product according to claim 1, characterized in that said polymers are selected from collagen derivatives, polyalkylene glycols, especially polyethylene glycols, polyglycerols, alginates, carrageenan, pectins, gums, cellulose derivatives, polyvinyl alcohols, polyvinyl pyrrolidones and derivatives thereof, and/or dextran.

### Claim 3 (depends on 1)

The sympathomimetic-free medicinal product according to claim 1, characterized by further containing panthenol.

### Claim 4 (depends on 1)

The sympathomimetic-free medicinal product according to claim 1, characterized by containing said humectant in an amount of from 0.1 to 5% by weight.

### Claim 5 (depends on 1)

The sympathomimetic-free medicinal product according to claim 1, characterized by further additionally containing common salt and/or sea salt.

### Claim 6 (depends on 1)

The sympathomimetic-free medicinal product according to claim 1, characterized by additionally containing essential oils.

### Claim 7 (depends on 1)

The sympathomimetic-free medicinal product according to claim 1, characterized by further containing pH control agents and/or tonicizing agents.

### Claim 8 (depends on 1)

The sympathomimetic-free medicinal product according to claim 1 in the form of an aqueous solution.

### Claim 9 (depends on 1)

Use of a sympathomimetic-free medicinal product according to claim 1 for preparing an agent for treating irritations of the nasal mucosa caused by a cold, by hay fever, a dry nose and/or sympathomimetic dependence.

### Claim 10 (depends on 9)

The use according to claim 9 in the form of drops, sprays and/or rinses.

### Claim 11 (depends on 4)

The sympathomimetic-free medicinal product according to claim 4, wherein said humectants is in an amount of 0.5-2% by weight based on total weight of the product.

### Claim 12 (depends on 6)

The sympathomimetic-free medicinal product according to claim 6, wherein said essential oil includes thyme oil, eucalyptus oil, and/or sage oil.

### Claim 13 (depends on 7)

The sympathomimetic-free medicinal product according to claim 7, wherein said tonicizing agent includes glucose, sorbitol, mannitol and/or xylitol.

### Claim 14 (depends on 2)

The sympathomimetic-free medicinal product according to claim 2, wherein said gums include tragacanth gum and/or gum Arabic.

### Claim 15 (depends on 2)

The sympathomimetic-free medicinal product according to claim 2, wherein said cellulose derivatives include cellulose ethers and/or cellulose esters.