# US 2013/0156824 A1 · Protective wound dressing device for oral and pharyngeal space

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- Number: US 2013/0156824 A1
- Document ID: US20130156824A1
- Status: Published application
- Kind: A1
- Application number: 13/768,033
- Filed: 2013-02-15
- Published: 2013-06-20
- Earliest claimed: 2011-08-25
- Assignees: Ethicon, Inc.
- Inventors: Scott Alan Keplinger
- Web page: https://patentgrep.com/patent/US20130156824A1

## CPC

- A61L 26/0052: {Mixtures of macromolecular compounds}
- A61F 13/122: {specially adapted for the face}
- A61L 15/24: Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds; Derivatives thereof {(A61L15/225 takes precedence)}
- A61L 15/32: Proteins, polypeptides; Degradation products or derivatives thereof, e.g. albumin, collagen, fibrin, gelatin {(A61L15/225 takes precedence)}
- A61L 15/58: Adhesives
- A61L 15/62: {Compostable,} hydrosoluble or hydrodegradable materials
- A61L 15/64: specially adapted to be resorbable inside the body
- A61L 24/06: obtained by reactions only involving carbon-to-carbon unsaturated bonds {(A61L24/043, A61L24/046 take precedence)}
- A61L 26/0014: {obtained by reactions only involving carbon-to-carbon unsaturated bonds}
- A61L 26/0038: {Gelatin}
- A61P 17/02: for treating wounds, ulcers, burns, scars, keloids, or the like
- A61L 2430/36: for embolization or occlusion, e.g. vaso-occlusive compositions or devices
- A61L: METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES (preservation of bodies or disinfecting characterised by the agents employed A01N; preserving, e.g. sterilising, food or foodstuffs A23; preparations for medical, dental or toiletry purposes A61K)
- A61F: FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS (dental prosthetics A61C)
- A61P: SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

## Abstract

The present invention provides a wound dressing comprising a tessellated water-soluble molding matrix comprised of a polymer selected from the group consisting of polyvinyl alcohol, gelatin, and mixtures thereof and a 1,1-disubstituted ethylene monomer. The present invention further provides methods of using the wound dressing and kits containing the wound dressing.

## Claims

### Claim at position 1

1-5. (canceled)

### Claim 6

A method of treating a wound comprising:
(1) applying a 1,1-disubstituted monomer to a wound and embedding a tessellated water-soluble molding matrix comprised of a polymer selected from the group consisting of polyvinyl alcohol, gelatin, and mixtures thereof in said 1,1-disubstituted ethylene monome;
(2) polymerizing the 1,1-disubstituted ethylene monomer; and
(3) dissolving said water-soluble molding matrix leaving a molded polymer applied to said wound.

### Claim 7 (depends on 6)

The method of claim 6 wherein said 1,1-disubstituted ethylene monomer comprises a cyanoacrylate.

### Claim 8 (depends on 6, 7)

The method of claim 7 wherein said cyanoacrylate is selected from the group consisting of ethyl cyanoacrylate, n-butyl cyanoacrylate, 2-octyl cyanoacrylate, methoxyethyl cyanoacrylate, ethoxyethyl cyanoacrylate, dodecyl cyanoacrylate, 2-ethylhexyl cyanoacrylate, butyl cyanoacrylate, 3-methoxybutyl cyanoacrylate, 2-butoxyethyl cyanoacrylate, 2-isopropoxyethyl cyanoacrylate, 1-methoxy-2-propyl cyanoacrylate, hexyl cyanoacrylate, butyl lactoyl cyanoacrylate, butyl glycolcyl cyanoacrylate, ethyl lactoyl cyanoacrylate, and ethyl glycoloyl cyanoacrylate. method of claim 6 wherein the tessellated water-soluble molding matrix is comprised of cells measuring less than about 5 mm in any given dimension.

### Claim 10 (depends on 6)

The wound dressing of claim 6 wherein the tessellated water-soluble molding matrix is comprised of cells measuring less than about 3 mm in any given dimension.

### Claim at position 6

11-15. (canceled)

### Claim 16

A method of treating a wound comprising:
(1) applying a tessellated water-soluble molding matrix comprised of a polymer selected from the group consisting of polyvinyl alcohol, gelatin, and mixtures thereof to a wound and applying a 1,1-disubstituted ethylene monomer to the wound filling at least a portion of at least one cell of the water-soluble molding matrix;
(2) polymerizing the 1,1-disubstituted ethylene monomer; and
(3) dissolving said water-soluble molding matrix leaving a molded polymer applied to said wound.

### Claim 17 (depends on 16)

The method of claim 16 wherein said 1,1-disubstituted ethylene monomer comprises a cyanoacrylate.

### Claim 18 (depends on 17)

The method of claim 17 wherein said cyanoacrylate is selected from the group consisting of ethyl cyanoacrylate, n-butyl cyanoacrylate, 2-octyl cyanoacrylate, methoxyethyl cyanoacrylate, ethoxyethyl cyanoacrylate, dodecyl cyanoacrylate, 2-ethylhexyl cyanoacrylate, butyl cyanoacrylate, 3-methoxybutyl cyanoacrylate, 2-butoxyethyl cyanoacrylate, 2-isopropoxyethyl cyanoacrylate, 1-methoxy-2-propyl cyanoacrylate, hexyl cyanoacrylate, butyl lactoyl cyanoacrylate, butyl glycolcyl cyanoacrylate, ethyl lactoyl cyanoacrylate, and ethyl glycoloyl cyanoacrylate.

### Claim 19 (depends on 16)

The method of claim 16 wherein the tessellated water-soluble molding matrix is comprised of cells measuring less than about 5 mm in any given dimension.

### Claim 20 (depends on 16)

The wound dressing of claim 16 wherein the tessellated water-soluble molding matrix is comprised of cells measuring less than about 3 mm in any given dimension.
