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US 2013/0123183 A1Published application
Anti-tumor Fibrillar Human Serum Albumin Methods and Compositions
AssigneeAcademia Sinica
InventorsShu-Mei Liang, Chi-Ming Liang
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Abstract
Fibrillar human serum albumin was shown to be effective in the treatment of various types of cancers. Methods and compositions are disclosed for using fibrillar human serum albumin as a medicament to treat subjects having cancer.
Claims22
A composition comprising:
- fibrillar human serum albumin and a pharmaceutically acceptable carrier.
A method comprising:
- administering to a subject having cancer a therapeutically effective amount of fibrillar human serum albumin.
A method comprising:
- manufacturing a composition useful in the treatment of cancer, the medication comprising fibrillar human serum albumin and a pharmaceutically acceptable carrier.
The method 9, wherein the fibrillar human serum albumin is manufactured by:
- dissolving human serum albumin in a detergent solution;
- applying the dissolved human serum albumin through a gel filtration column with a pore size that can separate proteins of 70 kDa molecular weight and above;
- removing the human serum albumin from the column;
- and
- dialyzing the solution against phosphate buffered saline to remove the SDS.
2 more elements
A method comprising:
- providing a therapeutically effective amount of fibrillar serum albumin for use in a subject having cancer.
Dependencies are inferred from the claim text.