Method for Manufacturing Sterile Flexible Bags Filled with a Product, Particularly with a Therapeutic Liquid, and Corresponding Bags

Method of manufacturing sterile flexible bags filled with a filling product comprising a therapeutic liquid, each said bag including two sheets connected together over their entire periphery and being provided with a valve making it possible to withdraw the product from the bag, the method comprising:

• a) providing valves which each include a base and a part, assembled together,
• b) placing the valves by application of each base directly onto a first flexible film and wherein at least one of two faces of said first flexible film is sterilized, and
• c) forming bags by heat welding using at least said first flexible film in such a way that an interior volume of the bags is delimited by a face or faces of said film sterilized beforehand, and filling said bags with a filling product, wherein:
• before the placing of the valves, on the first flexible film tapping areas are defined by a needle where respectively the bases are to be applied,
• during the step of providing the valves the part is carried out as a tube:
• having a removable portion adepted to be removed in order to allow for access of the needle through the tube to said tapping area, and for which an open end is assembled to the base, and
• at the step of placing the valves, the bases are applied onto the first film at the locations of the tapping areas, by covering the tapping areas.