# US 2013/0096842 A1 · Glucose tolerance analyzer, glucose tolerance analyzing system, and storage medium > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 2013/0096842 A1 - Document ID: US20130096842A1 - Status: Published application - Kind: A1 - Application number: 13/652,756 - Filed: 2012-10-16 - Published: 2013-04-18 - Earliest claimed: 2011-10-17 - Assignees: Sysmex Corporation - Inventors: Toshiyuki SATO; Seiki OKADA; Takeyoshi FUJIWARA; Mariko YUNO; Shigenobu EGAWA - Web page: https://patentgrep.com/patent/US20130096842A1 ## CPC - A61B 5/150259: {Improved gripping, e.g. with high friction pattern or projections on the housing surface or an ergonometric shape} - A61B 5/14532: {for measuring glucose, e.g. by tissue impedance measurement} - A61B 5/14546: {for measuring analytes not otherwise provided for, e.g. ions, cytochromes} - A61B 5/1455: using optical sensors, e.g. spectral photometrical oximeters - A61B 5/150022: {for capillary blood or interstitial fluid} - A61B 5/150412: {Pointed piercing elements, e.g. needles, lancets for piercing the skin (blade-like piercing elements A61B5/150442)} - A61B 5/150969: {Low-profile devices which resemble patches or plasters, e.g. also allowing collection of blood samples for testing} - A61B 5/150984: {Microneedles or microblades} - A61B 5/15113: {Manually triggered, i.e. the triggering requires a deliberate action by the user such as pressing a drive button} - A61B 5/15117: {comprising biased elements, resilient elements or a spring, e.g. a helical spring, leaf spring, or elastic strap} - A61B 5/1513: {comprising linear sliding guides (comprising tooth-shaped elements A61B5/15132)} - A61B 5/1519: {comprising driving means, e.g. a spring, for propelling the piercing unit} - A61B 5/7475: {User input or interface means, e.g. keyboard, pointing device, joystick} - A61B 5/6824: {Arm or wrist} - A61B 2560/0456: Apparatus provided with a docking unit - A61B 2560/0487: Special user inputs or interfaces - A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D) ## Abstract A glucose tolerance analyzer comprising: an accepting section configured to accept inputs of information regarding a type of food or drink ingested by a subject, information regarding an intake amount of the food or drink, and information regarding an amount of glucose in the subject after the ingestion of the food or drink; an output section configured to output an analysis result of glucose tolerance; and a controller configured to: calculate a reference value for analyzing glucose tolerance of the subject based on the accepted information regarding the type of the food or drink ingested by the subject and the information regarding the intake amount of the food or drink, and based on a predetermined index regarding blood glucose increase due to food or drink; analyze the glucose tolerance of the subject based on the accepted information regarding the amount of glucose and based on the calculated reference value; and control the output section to output an obtained analysis result as an analysis result of glucose tolerance. ## Claims ### Claim 1 A glucose tolerance analyzer comprising: an accepting section configured to accept inputs of information regarding a type of food or drink ingested by a subject, information regarding an intake amount of the food or drink, and information regarding an amount of glucose in the subject after the ingestion of the food or drink; an output section configured to output an analysis result of glucose tolerance; and a controller configured to: calculate a reference value for analyzing glucose tolerance of the subject based on the accepted information regarding the type of the food or drink ingested by the subject and the information regarding the intake amount of the food or drink, and based on a predetermined index regarding blood glucose increase due to food or drink; analyze the glucose tolerance of the subject based on the accepted information regarding the amount of glucose and based on the calculated reference value; and control the output section to output an obtained analysis result as an analysis result of glucose tolerance. ### Claim 2 (depends on 1) The glucose tolerance analyzer of claim 1, wherein the index regarding blood glucose increase due to food or drink is a glycemic index. ### Claim 3 (depends on 1) The glucose tolerance analyzer of claim 1, wherein the accepted information regarding the amount of glucose is an area under blood glucose concentration-time curve (blood glucose AUC) or a value corresponding to the blood glucose AUC. ### Claim 4 (depends on 3) The glucose tolerance analyzer of claim 3, wherein the controller calculates the reference value in accordance with a calculation formula for calculating the reference value, and the calculation formula is a formula represented by: reference value(Th(AUC))=A+[B/(C/GL)] [wherein A represents a fasting-blood-glucose-based two-hour blood glucose AUC value, B represents a reference value corresponding to an increase in a blood glucose level, C represents a glycemic load corresponding to a given amount of glucose, and GL represents a glycemic load calculated based on a glycemic index corresponding to the food or drink ingested by the subject and the intake amount of the food or drink]. ### Claim 5 (depends on 1) The glucose tolerance analyzer of claim 1, wherein the accepted information regarding the amount of glucose is information regarding an amount of glucose in tissue fluid collected, after the ingestion of the food or drink, from skin of the subject on which a process for promoting extraction of the tissue fluid from the skin has been performed. ### Claim 6 (depends on 5) The glucose tolerance analyzer of claim 5, wherein the tissue fluid is tissue fluid collected by being accumulated in a collector which is in contact with the skin of the subject. ### Claim 7 (depends on 6) The glucose tolerance analyzer of claim 6, wherein the amount of glucose is an amount of glucose in the tissue fluid collected in the collector, after two hours have elapsed since the ingestion of the food or drink, or after two hours have elapsed with the collector being in contact with the skin. ### Claim 8 (depends on 5) The glucose tolerance analyzer of claim 5, wherein the accepted information regarding the amount of glucose is a numerical value obtained by correcting the amount of glucose in the tissue fluid by an amount of inorganic ion in the tissue fluid. ### Claim 9 (depends on 8) The glucose tolerance analyzer of claim 8, wherein the inorganic ion is sodium ion. ### Claim 10 (depends on 1) The glucose tolerance analyzer of claim 1, wherein when the accepted information regarding the amount of glucose is information indicating that the amount of glucose exceeds the reference value, the controller generates an analysis result indicating that the subject has abnormal glucose tolerance. ### Claim 11 (depends on 1) The glucose tolerance analyzer of claim 1, wherein when the accepted information regarding the amount of glucose is information indicating that the amount of glucose is less than or equal to the reference value, the controller generates an analysis result indicating that the subject does not have abnormal glucose tolerance. ### Claim 12 (depends on 1) The glucose tolerance analyzer of claim 1, further comprising: an obtaining section configured to obtain information regarding nutrition guidance based on the accepted information regarding the type of the food or drink ingested by the subject and based on the analysis result generated by the controller, wherein the controller further controls the output section to output the information obtained by the obtaining section. ### Claim 13 A glucose tolerance analyzing system, comprising: a first information processing apparatus and a second information processing apparatus, wherein the first information processing apparatus comprises: an accepting section configured to accept inputs of information regarding a type of food or drink ingested by a subject, information regarding an intake amount of the food or drink, and information regarding an amount of glucose in the subject after the ingestion of the food or drink; a first transmission section configured to transmit the information accepted by the accepting section, to the second information processing apparatus; a first reception section configured to receive an analysis result of glucose tolerance of the subject from the second information processing apparatus; and an output section configured to output the analysis result received by the first reception section, and the second information processing apparatus comprises: a second reception section configured to receive the information transmitted from the first transmission section; a controller configured to calculate a reference value for analyzing the glucose tolerance of the subject based on the received information regarding the type of the food or drink ingested by the subject and the received information regarding the intake amount of the food or drink, and based on a predetermined index regarding blood glucose increase due to food or drink, and configured to analyze the glucose tolerance of the subject based on the received information regarding the amount of glucose received by the second reception section and based on the calculated reference value; and a second transmission section configured to transmit an analysis result obtained by the controller to the first information processing apparatus. ### Claim 14 (depends on 13) The glucose tolerance analyzing system of claim 13, wherein the index regarding blood glucose increase due to food or drink is a glycemic index. ### Claim 15 (depends on 13) The glucose tolerance analyzing system of claim 13, wherein the received information regarding the amount of glucose is an area under blood glucose concentration-time curve (blood glucose AUC) or a value corresponding to the blood glucose AUC. ### Claim 16 (depends on 15) The glucose tolerance analyzing system of claim 15, wherein the controller calculates the reference value in accordance with a calculation formula for calculating the reference value, and the calculation formula is a formula represented by: reference value(Th(AUC))=A+[B/(C/GL)] [wherein A represents a fasting-blood-glucose-based two-hour blood glucose AUC value, B represents a reference value corresponding to an increase in a blood glucose level, C represents a glycemic load corresponding to a given amount of glucose, and GL represents a glycemic load calculated based on a glycemic index corresponding to the food or drink ingested by the subject and the intake amount of the food or drink]. ### Claim 17 (depends on 13) The glucose tolerance analyzing system of claim 13, wherein the received information regarding the amount of glucose is information regarding an amount of glucose in tissue fluid collected, after the ingestion of the food or drink, from skin of the subject on which a process for promoting extraction of the tissue fluid from the skin has been performed. ### Claim 18 A glucose tolerance analyzing method, comprising: an accepting step of accepting inputs of information regarding a type of food or drink ingested by a subject, information regarding an intake amount of the food or drink, and information regarding an amount of glucose in the subject after the ingestion of the food or drink; an output step of outputting an analysis result of glucose tolerance; and a control step of: calculating a reference value for analyzing glucose tolerance of the subject based on the accepted information regarding the type of the food or drink ingested by the subject and the accepted information regarding the intake amount of the food or drink, and based on a predetermined index regarding blood glucose increase due to food or drink; analyzing the glucose tolerance of the subject based on the accepted information regarding the amount of glucose and based on the calculated reference value; and controlling an obtained analysis result to be outputted in the output step as an analysis result of glucose tolerance. ### Claim 19 (depends on 18) The glucose tolerance analyzing method of claim 18, wherein the index regarding blood glucose increase due to food or drink is a glycemic index. ### Claim 20 A non-transitory storage medium having stored thereon computer-executable programs executed by at least one processor of a computer system which is connected to an output device and an input device, the programs controlling the at least one processor to perform the steps of: controlling an accepting section to accept, via the input device, inputs of information regarding a type of food or drink ingested by a subject, information regarding an intake amount of the food or drink, and information regarding an amount of glucose in the subject after the ingestion of the food or drink; calculating a reference value for analyzing glucose tolerance of the subject based on the accepted information regarding the type of the food or drink ingested by the subject and the accepted information regarding the intake amount of the food or drink, and based on a predetermined index regarding blood glucose increase due to food or drink; analyzing the glucose tolerance of the subject based on the accepted information regarding the amount of glucose accepted by the accepting section and based on the calculated reference value; and controlling the output device to output an obtained analysis result.