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US 2013/0096836 A1Published application
Automated total body albumin analyzer
AssigneeDaxor Corp.
InventorsJoseph FELDSCHUH, Jonathan FELDSCHUH
Life of this patent
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Abstract
A computer-based method for automatically determining total body albumin of a living being based on the calculated intravascular albumin, the calculated observed ratio of amount of albumin in the intravascular system to amount of albumin in the extravascular system at the first time, and the baseline of expected ratio of amount of albumin in the intravascular system to amount of albumin in the extravascular system at the first time.
Claims11
A computer-based method for automatically determining total body albumin of a living being comprising the steps of:
- determining a baseline of expected ratio of amount of albumin in an intravascular system of the living being to amount of albumin in an extravascular system of the living being;
- determining albumin concentration of the living being;
- calculating, using one or more processors, plasma volume of the living being based on detected counts of radio-labeled albumin injected into the living being;
- calculating, using one or more processors, an amount of intravascular albumin within the living being based on the calculated plasma volume and the determined albumin concentration;
- calculating, using one or more processors, an observed ratio of amount of albumin in the intravascular system of the living being to amount of albumin in the extravascular system of the living being at a first time after injecting the radio-labeled albumin into the living being;
- and
- calculating, using one or more processors, the total body albumin of the living being based on the calculated intravascular albumin, the calculated observed ratio of amount of albumin in the intravascular system of the living being to amount of albumin in the extravascular system of the living being at the first time, and the baseline of expected ratio of amount of albumin in the intravascular system of the living being to amount of albumin in the extravascular system of the living being at the first time.
4 more elements
An automated total body albumin analyzer comprising:
- means for receiving input of first data related to a baseline of expected ratio of amount of albumin in an intravascular system of the living being to amount of albumin in an extravascular system of the living being;
- means for receiving input of second data related to albumin concentration of the living being;
- means for calculating plasma volume of the living being based on detected counts of radio-labeled albumin injected into the living being;
- means for calculating an amount of intravascular albumin within the living being based on the calculated plasma volume and the albumin concentration of the living being;
- means for calculating an observed ratio of amount of albumin in the intravascular system of the living being to amount of albumin in the extravascular system of the living being at at least one time after injecting the radio-labeled albumin into the living being;
- and
- means for calculating the total body albumin of the living being based on the calculated intravascular albumin, the calculated observed ratio of amount of albumin in the intravascular system of the living being to amount of albumin in the extravascular system of the living being at the at least one time, and the baseline of expected ratio of amount of albumin in the intravascular system of the living being to amount of albumin in the extravascular system of the living being at the at least one time.
4 more elements
A system for automatically determining total body albumin of a living being, comprising:
- one or more data processing apparatus;
- and
- a computer-readable medium coupled to the one or more data processing apparatus having instructions stored thereon which, when executed by the one or more data processing apparatus, cause the one or more data processing apparatus to perform a method comprising:
- receiving first data related to a determined baseline of expected ratio of amount of albumin in an intravascular system of the living being to amount of albumin in an extravascular system of the living being;
- receiving second data related to determined albumin concentration of the living being;
- calculating plasma volume of the living being by detecting counts of radio-labeled albumin injected into the living being;
- calculating an amount of intravascular albumin within the living being based on the determined plasma volume and the determined albumin concentration;
- calculating an observed ratio of amount of albumin in the intravascular system of the living being to amount of albumin in the extravascular system of the living being at a first time after injecting the radio-labeled albumin into the living being;
- and
- calculating the total body albumin of the living being based on the calculated intravascular albumin, the calculated observed ratio of amount of albumin in the intravascular system of the living being to amount of albumin in the extravascular system of the living being at the first time, and the baseline of expected ratio of amount of albumin in the intravascular system of the living being to amount of albumin in the extravascular system of the living being at the first time.
7 more elements
A computer-based method for automatically determining a preliminary value for the total body albumin of a living being comprising the steps of:
- determining albumin concentration of the living being;
- calculating, using one or more processors, plasma volume of the living being based on detected counts of radio-labeled albumin injected into the living being;
- calculating, using one or more processors, an amount of intravascular albumin within the living being based on the calculated plasma volume and the determined albumin concentration;
- and
- calculating, using one or more processors, the total body albumin of the living being based on the calculated intravascular albumin and an average value for the ratio of the amount of albumin in the intravascular system to total body albumin of the living being.
2 more elements
Dependencies are inferred from the claim text.