Hydrodissection Material with Reduced Migration
OwnerChristopher L. Brace, James L. Hinshaw +5inventors
InventorsChristopher L. Brace, James L. Hinshaw, Meghan G. Lubner, Anthony J. Sprangers, Alexander D. Johnson, Patrick R. Cassidy, Sean R. Heyman
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Abstract
A hydrodissection material provides a flowable biocompatible material that increases in viscosity in situ to reduce material migration during an ablation procedure. One embodiment provides a material that increases in viscosity at normal body temperatures to permit injection using a standard hypodermic needle.
Claims20
A method of tumor treatment comprising the steps of:
- (1) introducing a biocompatible gelable liquid in a liquid phase between a first and second tissue region to separate the regions;
- (2) converting the liquid phase gel to a gel phase having a substantially greater viscosity to resist migration from between the first and second tissue regions;
- and
- (3) applying a destructive agent to the first tissue to destroy a tumor portion thereof;
- wherein the separation of the first and second tissue is selected to protect the second tissue from the destructive agent applied to the first tissue.
A hydrodissection material for providing a barrier between two tissue regions, one subject to the application of a destructive agent, the hydrodissection material comprising a biocompatible gelable liquid having a gel phase viscosity of greater than 18 centiStokes at body temperature and a liquid phase viscosity of less than 18 centiStokes at room temperature to be introducible through a hypodermic needle between tissue regions to create barriers there between.
Dependencies are inferred from the claim text.