Chiral diene ligands, a fabrication method thereof and applications thereof

A method for fabricating a chiral diene ligand, comprising

• Step (1)—a first oxidation step:
• undertaking an oxidation reaction of a cyclic reactant and chromium trioxide in an acidic environment to form a keto ester;
• Step (2)—a saponification step:
• undertaking a reaction of said keto ester and a basic material to form a saponified keto ester;
• Step (3)—a second oxidation step:
• undertaking a reaction of said saponified keto ester and an oxidizing agent to form a dikentone;
• Step (4)—a deprotonation step:
• undertaking a reaction of said dikentone, KHMDS (potassium hexamethyl disilazide) and a Comins' reagent to form trifluoromethanesulfonate;
• and
• Step (5)—a cross-coupling step:
• undertaking a cross-coupling reaction of said trifluoromethanesulfonate in a basic environment,
• wherein said chiral diene ligand is expressed by a structural formula:
• wherein R is a functional group selected from a group consisting of C6H5, 4-Me-C6H4, 4-Bu-C6H4, 4-Ph-C6H4, 1-nathphyl, 2-nathphyl, 4-F—C6H4, 4-Cl—C6H4, 4-NO2—C6H4, alkenyl groups, alkynyl groups, and carbonyl groups.