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US 2013/0096169 A1Published application
Treatment of cancer with bio and chemotherapy
AssigneeCedars-Sinai Medical Center
InventorJohn S. Yu
Life of this patent
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Abstract
This invention relates to compositions and methods utilizing a chemotherapeutic drug and 6-bromoindirubin3′-oxime (BIO) for the treatment of cancer, including glioblastoma multiforme. The present invention demonstrates that BIO works synergistically with chemotherapeutic drugs to increase the cytotoxic effects of these drugs in glioma cells.
Claims10
A method for treating cancer in a subject in need thereof, comprising:
- providing a glycogen synthase kinase-3 (“GSK-3”) antagonist and/or Wnt canonical pathway agonist and a chemotherapeutic drug;
- and
- administering the GSK-3 antagonist and/or Wnt canonical pathway agonist and the chemotherapeutic drug to the subject to treat the cancer.
10-27. (canceled)
Dependencies are inferred from the claim text.