Method for enhancing learning and memory impaired by neurodegenerative disorders and compounds and compositions for effecting the same
AssigneeThe Board of Trustees of the Leland Stanford Junior University
InventorsMehrdad Shamloo, Mehrdad Faizi, William Mobley
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Abstract
A method for enhancing learning or memory of both in a mammal having impaired learning or emory of both from a neuro-degenerative disorder, which entails the step of administering at least one compound or a salt thereof which is a β1-adrenergic receptor agonist, partial agonist or receptor ligand in an amount effective to improve the learning or memory or both of said mammal.
Claims11
1) A method for enhancing learning or memory or both in a mammal having impaired learning or memory or both from a neuro-degenerative disorder, which comprises the step of administering at least one compound or a salt thereof which is a β1-adrenergic receptor agonist, partial agonist or receptor ligand in an amount effective to improve said learning or memory or both of said mammal.
A method of comprehensively phenotyping Ts65Dn mice to identify behavioral abnormalities in learning, memory and social behavior, which comprises subjecting Ts65Dn mice to tests in order to correlate behavioral phenotypic traits with trisomy 16.
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