Protein hydrolysate enriched in peptides inhibiting dpp-iv and their use
AssigneeCampina Nederland Holding B.V.
InventorJan-Willem Pieter BOOTS
Life of this patent
Estimating the term…
Abstract
Disclosed is a protein hydrolysate having DPP-IV inhibiting activity, the hydrolysate being enriched in peptides having a length of 2-8 amino acids comprising at least one proline residue, an isolated peptide derivable from such a protein hydrolysate, or a mixture thereof, and the use of such protein hydrolysate or isolated peptide for the manufacture of a medicament, food supplement, beverage or food product for prophylaxis and/or treatment of a DPP-IV mediated condition, in particular chosen from the group of obesity, type 2 diabetes mellitus and an immunological disorder.
Claims10
A protein hydrolysate having DPP-IV inhibiting activity, the hydrolysate comprising (i) 20 and 80 wt. %, based on total protein, of peptides having a length of 2-8 amino acids, and (ii) one or more peptides having 3-7 amino acids in which at least one proline residue is flanked by leucine, valine or phenylalanine.
An isolated peptide or mixture of peptides comprising a peptide selected from the group consisting of LPL, MPLW, GPFP, PLLQ, KVLP, LPQYL, LPVPQ, VPYPQ, VPLGTQ, and LPVPQK, or a mixture of two or more thereof.
Dependencies are inferred from the claim text.