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US 2013/0095262 A2Published application
Cyanoacrylate Adhesive Compositions, Methods of Sterilization of the Compositions, and Articles of Manufacture Containing Such Compositions
AssigneeChemence Medical, Inc.
InventorCarlos Morales
Life of this patent
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Abstract
The viscosities of 2-cyanoacrylate adhesive compositions are adjusted by the addition of polymeric thickeners to a preferred initial viscosity that will not increase significantly when sterilized by heating them at a temperature of no greater than about 110° C. for no more than about 120 minutes. Articles of manufacture are vials or squeezable tubes containing these compositions.
Claims5
A cyanoacrylate adhesive composition, comprising:
- at least one 2-cyanoacrylate monomer;
- and
- at least one polymeric thickener in an amount
- establishing an initial viscosity that will not significantly increase when the composition is sterilized at a temperature no greater than approximately 110° C. for a period of time sufficient to sterilize the composition.
1 more element
An article of manufacture, comprising:
- a container
- packed with a mixture of
- at least one 2-cyanoacrylate monomer;
- and
- at least one polymeric thickener in an amount establishing a viscosity that will not significantly increase when the mixture is sterilized;
- the container then being sealed;
- and
- heated to a temperature of between about 100° C. and about 110° C. for a period of time between about 60 minutes and about 120 minutes.
5 more elements
An article of manufacture, comprising:
- a container comprised of a material taken from the list of:
- (a) aluminum,
- (b) plastic, and
- (c) glass;
- packed with a mixture of about 3.5% by weight of polyoctyl-2-cyanoacrylate, about 100 ppm sulfur dioxide, and about 1000 ppm butylated hydroxyanisole (BHA), all dissolved in the balance percentage by weight of octyl-2-cyanoacrylate monomer, then sealed;
- and
- the sealed container heated to a temperature of between about 100° C. and about 110° C. for a period of time between about 60 minutes and 120 minutes, establishing a sterile adhesive having a viscosity of in the range of about 400 centipoises to about 600 centipoises.
4 more elements
Dependencies are inferred from the claim text.