Cosmetic composition containing retinol stabilized by porous polymer beads and nanoemulsion
AssigneeAct, Inc.
InventorsSang-Ho Jeong, Ji-Hyun Son, Su-Jin Jang, Yun-Jeong Kim, Jong-Woo Cheon
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Abstract
The present invention relates to a method for stabilizing retinol (Vitamin A), an unstable fat-soluble material, to use the same in cosmetics. The present invention provides an anti-inflammatory and skin wrinkle reducing cosmetic composition containing retinol stabilized by nano-emulsification, wherein a retinol polymer nanocapsule formed by capturing retinol with porous polymer particles is nano-emulsified by a mung bean MCT (medium chain triglyceride) extract and lecithin for stabilizing retinol.
Claims9
An anti-inflammatory and skin wrinkle reducing cosmetic composition containing retinol stabilized by nano-emulsification, wherein a retinol polymer nanocapsule formed by adsorbing retinol with mesoporous polymer beads is nano-emulsified to a size of 50˜200 nm using a mung bean MCT (medium chain triglyceride) extract and lecithin to stabilize the retinol.
A method of stabilizing retinol, comprising the steps of:
- (A) (a1) adding mesoporous polymer beads having a particle size of 50 nm to 500 nm to ethanol to prepare a first mixture, stirring the first mixture, mixing an antioxidant (butylated hydroxytoluene) with the first mixture to prepare a second mixture, and then dissolving the second mixture, (a2) adding retinol (vitamin A) to the second mixture to prepare a third mixture, completely dissolving the third mixture, mixing the third mixture with distilled water to prepare a mixed solution, and then stirring the mixed solution, (a3) filtering and drying the mixed solution under reduced pressure to prepare a retinol-adsorbed polymer nanocapsule;
- (B) (b1) heating glycerin, and then mixing the heated glycerin with tocopheryl acetate, butylated hydroxyanisole and a mung bean MCT extract to prepare a fourth mixture while dissolving the fourth mixture, (b2) adding cholesterol to the fourth mixture to prepare a fifth mixture, dissolving the fifth mixture, and then adding the retinal-adsorbed polymer nanocapsule to the fifth mixture to prepare a sixth mixture, (b3) adding hydrogenated lysolecithin to the sixth mixture to prepare a seventh mixture, dissolving the seventh mixture, adding purified water to the seventh mixture to prepare a mixed solution, and then stirring the mixed solution to prepare a nano-emulsion composition;
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- (C) forming the nano-emulsion composition into a nano-emulsion having a size of 50˜200 nm using a high-pressure homogenizer (microfluidizer) to stabilize retinal.
Dependencies are inferred from the claim text.