Stabilized active compound
AssigneePrayon
InventorsKhadija Tantaoui Elaraqi, Guy Broze, Audrey Leruite
Life of this patent
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Abstract
Stable solid compositions have a first carrier and an adsorbate having at least one active component, such as, a vitamin D derivative and a hydrophobic stabilizer thereof, wherein the first carrier is a calcium phosphate or derivatives thereof having a solubility in water lower than 0.1 wt % at room temperature.
Claims16
A stable solid composition comprising a first carrier and an adsorbate adsorbed thereon, the adsorbate comprising at least one active component and a hydrophobic stabilizer thereof, wherein the carrier is a calcium phosphate, or derivatives thereof, having a solubility in water lower than 0.1 wt % at room temperature, and the at least one active component is soluble in the hydrophobic stabilizer.
A method for preparation of a stable solid composition, the method comprising:
- dispersing at least one active component into a hydrophobic stabilizer to form an adsorbate,
- contacting said adsorbate with a first carrier, and adsorbing the adsorbate onto the first carrier to form a composition,
- homogenising the composition obtained in the previous step, to form a stable solid composition,
- wherein the first carrier is a calcium phosphate, or derivatives thereof, having a solubility in water lower than 0.1 wt % at room temperature.
Dependencies are inferred from the claim text.