Preparation for Transnasal Application
AssigneeShin Nippon Biomedical Laboratories, Ltd.
InventorsRyoichi Nagata, Shunji Haruta
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Abstract
Disclosed is a preparation for transnasal application, which has improved fluidability. Specifically disclosed is a preparation for transnasal application, which comprises at least a complex comprising a fluidability-improving component comprising a first crystalline cellulose (A) having specified powder properties, tricalcium phosphate (B) having specified powder properties, and a second crystalline cellulose (C) having specified powder properties or a starch (D) having specified powder properties, and physiologically active substance.
Claims11
A method for manufacturing a set of capsules containing a powdery formulation for nasal administration comprising:
- (a) homogeneously mixing a powdery drug with a powdery carrier comprising a first crystalline cellulose;
- and
- (b) filling a set of capsules with the powdery formulation, wherein the standard deviation in fill uniformity is less than 3.5%.
Dependencies are inferred from the claim text.