Method For Controlling And Accelerating Differentiation Of Stem Cells Using Graphene Substrates
AssigneeNational University of Singapore
InventorsBarbaros Oezyilmaz, Giorgia Pastorin
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Abstract
The invention relates to methods for directing differentiation of stem cells comprising graphene. In additional embodiments, the invention relates to methods for repairing and improving bone tissue functions comprising accelerating differentiation in stem cell growth by exposing stem cells to graphene and transplanting the graphene with the exposed stem cells in the tissue at the site of repair.
Claims20
A method of directing stem cell differentiation in the absence of growth factors or external stimulation, comprising:
- placing stem cells on a graphene substrate and exposing to a culture media for a period of time sufficient to allow the stem cells to differentiate in cells of interest in the absence of growth factors or external stimulation.
A method of repairing and improving bone tissue function comprising directing stem cell differentiation by placing the stem cells on graphene in the absence of growth factors or external stimulation and transplanting the differentiated stem cells in the tissue at the site of repair.
A composition for accelerating differentiation of stem cells comprising graphene on an implantable, biocompatible scaffold for support of tissue growth.
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Dependencies are inferred from the claim text.