Methods for regenerating skeletal muscle
OwnerChristopher Malcuit, Tanja Dominko +3inventors
InventorsChristopher Malcuit, Tanja Dominko, Raymond Lynn Page, George D. Pins, Jennifer Makridakis
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Abstract
An engineered muscle construct in the form of a braided collagen microthread scaffold is provided. The microthread scaffold can be used with or without cells as engineered skeletal muscle. The microthread scaffold can also be used to promote cell attachment and growth to deliver cells to a large muscle defect to stimulate muscle regeneration. Methods for making a muscle construct, seeding cells onto microthread scaffolds and treating muscle defects are also provided.
Claims16
A composition comprising a polymer configured as a plurality of microthreads, each having a leading end and a trailing end for use as a therapeutic agent or device for repairing muscle tissue defects.
Dependencies are inferred from the claim text.