Methods for Treating Vascular Leak Syndrome and Cancer
AssigneeAerpio Therapeutics Inc.
InventorsKevin Peters, Robert Shalwitz
Life of this patent
Estimating the term…
Abstract
Disclosed are methods for treating Vascular Leak Syndrome and preventing cancer metastasis. Further disclosed are methods for treating vascular leakage due to inflammatory diseases, sepsis, cancer or the presence of pathogens.
Claims25
A method for treating or preventing vascular leak syndrome in a patient comprising administering to the patient a composition comprising an effective amount of an HPTPO-ECD binding agent or a pharmaceutically acceptable salt thereof.
A method for determining the course of treatment for a patient suffering from vascular leak syndrome, comprising:
- a) administering to a patient a composition comprising an effective amount of an HPTPβ-ECD binding agent;
- b) monitoring the level of angiopoietin-2 present in the patient during the course of treatment;
- and
- c) discontinuing treatment when the angiopoietin-2 level returns to within a normal range.
A method for treating or preventing metastasis in a patient with cancer, by administering to a patient having cancer, a composition comprising an effective amount of an HPTPβ-ECD binding agent or a pharmaceutically acceptable salt thereof.
A method for stabilizing the vasculature of a patient in need thereof, comprising administering to the patient a composition comprising an effective amount of an HPTPβ-ECD binding agent or a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.