Compositions and methods to prevent cancer with cupredoxins
AssigneeThe Board of Trustees of the University of Illinois
InventorsTapas Das Gupta, Ananda Chakrabarty, Craig Beattie, Tohru Yamada
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Abstract
The present invention discloses methods and materials for delivering a cargo compound into a cancer cell. Delivery of the cargo compound is accomplished by the use of protein transduction domains derived from cupredoxins. The cargo compound may be a nucleic acid and specifically a DNA, RNA or anti-sense. The invention further discloses methods for treating cancer and diagnosing cancer.
Claims69
An isolated peptide that is a variant, derivative or structural equivalent of a cupredoxin;
- and that can inhibit the development of premalignant lesions in mammalian tissue.
An isolated peptide that is a variant, derivative or structural equivalent of a cupredoxin;
- wherein the isolated peptide is coupled to a cargo compound and can selectively enter mammalian cancer cells.
Dependencies are inferred from the claim text.