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US 2013/0004594 A1Published application
Oral rehydration composition
AssigneeDrip Drop, Inc.
InventorEduardo P. Dolhun
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Abstract
Disclosed are oral rehydration compositions with sucrose, or alternatively fructose and glucose in a 1:1 ratio. The composition further comprises an osmolarity of below 250 mOsm/L, and sodium below 75 meq/L. Further disclosed are methods of treatment using the same.
Claims25
An oral rehydration composition, comprising:
- a) at least 40% w/w sucrose;
- b) between 3% w/w and 5% w/w sodium;
- c) between 0.1% w/w chloride and less than 1.5% w/w chloride;
- d) potassium, at a level less than 0.5% w/w;
- e) between 20% w/w and 30% w/w citric acid or citrate;
- and
- f) glucose, at a level less than 0.5% w/w;
- wherein the ratio of sodium to chloride is at least 5:1, and wherein, upon mixture with an effective amount of water, the composition has an osmolarity of between 230 mOsm/L and 240 mOsm/L.
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A method of treating dehydration in a subject in need thereof, comprising administering to the subject a composition of claim 1 or 22.
An oral rehydration composition, comprising:
- a) at least 40% w/w sucrose;
- and
- b) glucose, at a level less than 0.5% w/w;
- and
- c) sodium;
- chloride;
- potassium;
- and citric acid or citrate;
- wherein upon mixture with an effective amount of water, the composition comprises:
- i. between 50 meq/L sodium and 70 meq/L sodium;
- ii. between 3 mmol/L chloride and less than 10 mmol/L chloride;
- iii. a ratio of sodium to chloride of at least 5:1;
- iv. potassium, at a concentration less than 35 mmol/L;
- v. between 200 meq/L citric acid or citrate and 100 meq/L citric acid or citrate;
- and
- vi. an osmolarity of between 230 mOsm/L and 240 mOsm/L.
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Dependencies are inferred from the claim text.