Transgenic non-human animals
AssigneesAgriculture Victoria Services PTY LTD, Murray Goulburn Co-Operative Co., Limited
InventorsPeter Hobman, Matthew McDonagh, Benjamin Cocks, Angus Tester
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Abstract
The invention provides a non-human transgenic animal comprising a transgene encoding angiogenin and food products comprising or obtained from the non-human transgenic animal and uses thereof.
Claims26
A non-human transgenic animal comprising a transgene encoding angiogenin.
An expression cassette comprising a coding sequence for angiogenin operably linked to a heterologous mammalian tissue-specific promoter.
A method for producing a non-human transgenic animal comprising an angiogenin transgene, said method comprising:
- (a) introducing an angiogenin transgene into a single-celled embryo, forming a genetically modified embryo;
- and
- (b) transferring the genetically modified embryo into a recipient female of the same species as the embryo, wherein the genetically modified embryo develops into a transgenic animal in the female.
A method for producing a non-human transgenic animal comprising an angiogenin transgene, said method comprising:
- a) introducing an angiogenin transgene into a somatic cell, forming a genetically modified somatic cell comprising a genetically modified nucleus;
- b) transferring the genetically modified nucleus from the genetically modified somatic cell into a single-celled embryo, generating a genetically modified single-celled embryo;
- and
- c) transferring the genetically modified single-celled embryo into a recipient female of the same species as the embryo, wherein the genetically modified embryo develops into a transgenic animal in the female.
(canceled)
Dependencies are inferred from the claim text.