Tissue repair
AssigneeIntercytex Limited
InventorMike LEEK
Life of this patent
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Abstract
According to the invention there is provided a cosmetic method for the augmentation of subcutaneous or dermal tissue in a subject, which method comprises the steps of: (i) providing a suspension of autologous dermal fibroblasts; and (ii) injecting an effective volume of the suspension into tissue subadjacent to the subcutaneous or dermal tissue so that the tissue is augmented; wherein the fibroblasts are suspended in HYPOTHERMOSOL®, preferably HYPOTHERMOSOL®FRS.
Claims22
A method for the repair of a skin defect and/or soft tissue defect in a subject, which method comprises the steps of:
- (i) providing a suspension of autologous dermal fibroblasts;
- and
- (ii) injecting an effective volume of the suspension into tissue subadjacent to the skin defect and/or soft tissue defect so that the tissue is augmented, thereby repairing the skin defect and/or soft tissue defect,
- wherein the fibroblasts are suspended in a preservation medium having a pH of 7.6 and osmolality of ˜360, and comprising the following components:
- 6-hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid, Na+, K+, Ca2+, Mg2+, Cl−, H2PO4−, HCO3−, HEPES, Lactobionate, Sucrose, Mannitol, Glucose, Dextran-40, Adenosine and Glutathione.
A composition for repair of a skin defect and/or soft tissue defect in a subject, which comprises a suspension of autologous dermal fibroblasts in a preservation medium having a pH of 7.6 and osmolality of ˜360, and comprising the following components:
- 6-hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid, Na+, K+, Ca2+, Mg2+, Cl−, H2PO4−, HCO3−, HEPES, Lactobionate, Sucrose, Mannitol, Glucose, Dextran-40, Adenosine and Glutathione.
Dependencies are inferred from the claim text.